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diagnosis hematology causes anemia algorithm classification blood criticalcare oncology product reactions shock approach calculation coagulation dic disseminated factor7 factorvii fvii
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Approach to Anemia - Differential ... Loss • Acute Bleed ... Smear • Chronic Bleed ... • B12/Folate Deficiency ... • Aplastic Anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
RBC) Morphology Atlas ... Liver diseases, Bleeding ... RBC #Morphology #Atlas ... key #diagnosis #differential ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
- Overview Who ... ecchymoses, mucosal bleeding ... anemia, GATA2 deficiency ... , CTLA4 deficiency ... #diagnosis #management
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... • Marrow Aplasia ... • Acute Bleed ... • Early Iron Deficiency ... Algorithm #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron deficiency ... marrow failure: Aplastic ... loss: Trauma, Gl bleed ... cell anemia, G6PD deficiency ... #anemia #differential
Algorithm for managing FVII deficiency. *Mild bleeding history includes minor epistaxis, menorrhagia, gastrointestinal bleeding, joint and soft
managing FVII deficiency ... tissue and joint bleeds ... #FVII #deficiency ... Factor7 #Algorithm #management ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Coagulation (DIC) Overview ... Findings: • Bleeding ... thrombopoietin deficiency ... causes #treatment #management ... #hematology
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... • Hemorrhagic: bleeding ... RP bleed) • Hypovolemic ... Classification #diagnosis #management ... #differential #
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... • Hemorrhagic: bleeding ... RP bleed) • Hypovolemic ... Classification #diagnosis #management ... #differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are caused by bleeding ... Causes • Anemia • Aplastic ... or folic acid deficiency ... treatments • Copper deficiency ... blood count with differential
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