43 results
Allergic Contact Dermatitis 
- Erythematous, indurated, scaly plaques 
- T-cell mediated, delayed-type hypersensitivity response to exogenous
Allergic Contact ... T-cell mediated, delayed-type ... Contact #Dermatitis #Allergic ... #Allergy #Dermatology
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
cytokines Common causes ... infection - Allergic ... disease Rare causes ... + T cells) - Allergic ... arthritis, IgG4-related
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... • Acne • Allergy ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
anyone - Allergic ... - Delayed onset ... Eczematous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
released during an allergic ... Statistical error/delay ... Chickenpox Other Causes ... Differential #Diagnosis #causes ... #hematology #basophils
Causes of Leukocytosis and Leukopenia - Differential Diagnosis
 • Eosinophilia (AEC > 500, hypereosinophilia > 1500):
Causes of Leukocytosis ... hypereosinophilia > 1500): Allergic ... Differential #Diagnosis #causes ... #hematology
Vascular Skin Lesions - Differential Diagnosis Algorithm
 - Petechiae < 0.2 cm diameter
 - Purpura 0.2
Pressure - Small, dilated ... Vasculitis #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... • Alloimmune delayed ... Diagnosis #Algorithm #Causes ... #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... are asthma, allergy ... Differential #diagnosis #hematology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... lgE causes mast-cell ... Course: Days (delayed ... reactions #types #allergy