49 results
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
Evaluation of Hyperthyroidism ... Possibly Central Hypothyroidism ... of pregnancy, critical ... → Signs of ... ophthalmopathy → Graves' Disease
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
diagnosis of primary hypothyroidism ... is a neurologic manifestation ... of hypothyroidism ... #PhysicalExam #Hypothyroidism ... Reflexes #Delayed #Clinical
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Overview Clinical ... Manifestation of ... goiter (Graves' disease ... causes #diagnosis #differential ... endocrinology #signs
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
Characteristic clinical ... manifestations ... Increased risk of hypothyroidism ... PhysicalExam #Features #Signs ... #Manifestations
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
CLINICAL MANIFESTATIONS ... Autoimmune thyroid disease ... - Secondary hypothyroidism ... Insufficiency #Signs
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... appearing during the disease ... Infectious manifestations ... myelodysplastic #syndrome #differential ... dermatology #oncology #clinical
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... in GBA1 gene Clinical ... Manifestations ... #Gauchers #Disease ... #Diagnosis #Signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... Pathogenesis and Clinical ... rare, gestational diseases ... Secondary hyperthyroidism ... Signs/Symptoms:
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... dermatology #semiology #signs ... lesions #diagnosis #clinical ... #manifestations ... pathology #lesions #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Erythematosus - Diagnosis Manifestations ... (aPL) 30-45% Differential ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs