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diagnosis rheumatology treatment algorithm causes dermatology syndrome workup ana anemia antinuclear hepatology autoantibodies autoimmune blood classification coagulation diseases disorders erythematosus
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear Antibody ... Antineutrophil cytoplasmic antibodies ... Antineutrophil #antibodies ... #diagnosis #rheumatology ... #diseases
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... polyangiitis U1-RNP antibody ... Endomyseal antibody ... diagnosis #table #rheumatology ... #antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... or Anti-NucIear Antibody ... refers to antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Congenital Diseases ... and Autoimmune Diseases ... hemoglobinuria • Antibody-mediated ... #Diagnosis #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... • Blood smear: Differential ... Pouchelon #Warm #Antibody ... Anemia #diagnosis #management ... #treatment #rheumatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... B12 - Anti-IF Antibodies ... B12 - Anti-IF Antibodies ... • Liver Disease ... Algorithm #Causes #Hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... migrans • Lyme disease ... Sarcoidosis • Crohn's disease ... Antiphospholipid-antibody ... #skin #rashes #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Pleural Effusion - Differential ... Collagen vascular disease ... Gastrointestinal disease ... • Uremia • Meigs ... Diagnosis #Algorithm #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... PT, aPTT(liver disease ... anti-phospholipid antibodies ... bypass), LFT (liver disease ... Causes #Workup #hematology
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