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diagnosis treatment differential syndrome hematology lupus sle algorithm cardiology erythematosus fungal infectiousdiseases stills summary activetb adultonset anesthesia anesthesiology aosd checklist
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... calcinosis • Pulmonary ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... SSc: systemic sclerosis ... arthritis SLE : systemic ... Comparison #Table #Pulmonary ... #Rheumatology #
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Systemic Sclerosis ... : Diffuse skin disease ... , Pulmonary fibrosis ... (~93-95%), Pulmonary ... Autoantibodies #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... solid cancers • Systemic ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Evolution: Chronic disease ... #SLE #lupus #Systemic ... #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
• Homogeneous: Systemic ... ) • Speckled: Systemic ... • Peripheral: Systemic ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... • MCTD (SLE/systemic ... @AnnKumfer #Systemic ... Summary #diagnosis #rheumatology ... #management
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
ophtho referral • Systemic ... : • Systemic steroids ... : • Systemic steroids ... Syndrome #Treatment #management ... #pharmacology #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
highly inflammatory disease ... Adult-onset Still disease ... of underlying disease ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Management of interstitial lung disease (ILD)-associated with systemic sclerosis (SSc) Therapeutic indication: absolute decline in FVC >10%
Management of interstitial ... lung disease (ILD ... associated with systemic ... systemicsclerosis #SSc #pulmonary ... #indications #management
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