10 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... are present • Classic ... #Classification ... #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 1B: Weak Blockade ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Thrombocytosis: cells ... tourniquet while drawing ... 7) - principal cells ... #causes #potassium ... #high #pathophysiology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... pulmonary Langerhans cell ... #Differential #Causes
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... • 75-90% of cases ... monophasic Pathophysiology ... Abnormal in 50% of cases ... • Infectious causes
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... • Classic triad ... and other organ dysfunction ... leukocytosis, psychiatric disorders ... adrenoceptors, potentially leading
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... Non-compressive Spinal Cord Causes ... Vascular/Blockage ... Bowel and bladder dysfunction ... differential #algorithm
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
Pathogenesis of Select Causes ... neuromuscular disorders ... CNS neurons -> Dysfunction ... colonic mucosa, leading ... #constipation #pathophysiology
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
LCH is a rare disorder ... various tissues, leading ... Incidence: 4–5 cases ... • Endocrine Dysfunction ... therapies for cases