38 results
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Vaughan Williams Classification ... depolarization in fast AP cells ... depolarization in slow AP cells ... VaughanWilliams #Classification ... #Classes #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #differential #algorithm
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 1B: Weak Blockade ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... mast-cell degranulation ... antigens, leading ... T-cells recruit ... allergy #table #classification
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... Thrombocytosis: cells ... tourniquet while drawing ... 7) - principal cells ... #causes #potassium
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
malignant, pediatric cases ... • Classic triad ... and other organ dysfunction ... beta-adrenergic blockade ... adrenoceptors, potentially leading
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
countries (11-24 cases ... Americans (18-71 cases ... mortality: 9-14 cases ... dysfunction and ... symptoms are not caused
Increased Airway Pressure - Guidelines for Crises in Anaesthesia

Using these steps from start to end should
Consider potential causes ... POTENTIAL CAUSES ... neuromuscular blockade ... Consider potential causes ... Checklist #Diagnosis #Management
Mechanisms of Pain
Mixed - Nociceptive/Neuropathic
Nociceptive - Tissue Damage
 - Visceral - (From organ/cavity lining) Poorly localized,
Superficial - Well-localized ... - Deep - Less well-localized ... Burning, shooting, gnawing ... Differential #Diagnosis #Algorithm ... #Causes