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Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Vaughan Williams Classification ... - Summary Table ... Class III agents - Potassium ... #Medications #Classification ... #Summary #Table
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... : • MOA: Block ... repolarization CLASS 3 - Potassium ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Vaughan Williams Classification ... : • MOA: Block ... repolarization CLASS 3 - Potassium ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiseizure Drugs 
Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin
Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Sodium Channel Blockers ... Tiagabine, Vigabatrin Potassium ... AMPA Receptor Blocker ... pharmacology #comparison #table
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... : NSAIDs, Beta-Blockers ... #Hyperkalemia #Pathophysiology ... Pharmacology #Impaired #Potassium
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... - When digoxin blocks ... intracellular calcium causes ... Since digoxin blocks ... #Pharmacology #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
(NSAIDs, Beta-Blockers ... Angiotensin II Receptor Blockers ... Sodium-channel blockers ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Antiarrhythmic Medication Table

#Antiarrhythmic #Medications #Table #Classification #Classes #Cardiology #Pharmacology
Antiarrhythmic Medication Table ... #Medications #Table ... #Classification ... #Classes #Cardiology
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Diagnosis #Low #Potassium ... #Table #Classification ... #Causes
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Adenosine, Magnesium, Potassium ... #Medications #Classes ... #Classification