9 results
Causes of False Elevation and Reduction in HbA1c

== False Elevation ==
Decreased RBC turnover 
• Iron, B-12,
Causes of False ... Content • RBC Transfusions ... blood loss • Hemolytic ... #Decrease #Diagnosis ... #DM2 #Differential
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Crossmatch - involves testing ... Transfusion Thresholds ... Causes purpura & ... false negatives on testing ... #diagnosis #management
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Poorly controlled DM ... #differential #diagnosis ... #causes #potassium ... #high #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Tissue injury • Hemolysis ... intake • Blood transfusion ... of injection Decreased ... blockers - MCW Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Poorly controlled DM ... #differential #diagnosis ... #causes #potassium ... #high #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
LDH - Assess for hemolysis ... for increased or decreased ... infections are common causes ... #workup #diagnosis ... nephrotic #nephritic #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
injury, ischemia, hemolysis ... , transfusions), ... ↓insulin (DM, DKA ... only if no clear cause ... Treatment #potassium #nephrology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
LDH - Assess for hemolysis ... for increased or decreased ... infections are common causes ... disease #workup #diagnosis ... #nephrology #nephrotic
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... associated with DM ... disorders • Testing ... diazepam • EMG testing ... activity, typically decreased