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hematology diagnosis management blood bruising dic differential disseminated intravascular platelet procedures product reactions risk targets teg thrombocytopenia thromboelastogram thromboelastography transfusions
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... #diagnosis #causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Bleeding #Bruising ... #Causes #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Thresholds ... Causes purpura & ... cause of transfusion ... coagulopathy & ↑bleeding ... more likely to cause
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... algorithms and ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastogram #TEG #interpretation
Procedure Risks and Platelet Targets for Transfusion LOW RISK - Transfuse ≥ 20,000/uL • Paracentesis, EGD or
Procedure Risks and Platelet ... Targets for Transfusion ... Prophylactic variceal bleeding ... , Argon plasma coagulation ... #Transfusion #thresholds
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