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diagnosis clinical msk hematology radiology management orthopedics workup mri anemia endocrinology pathophysiology syndrome ultrasound hypercalcemia nephrology dermatology disease disorders fracture
Paget's Disease of Bone • Characterized by an ↑ rate of bone turnover with both excessive
Paget's Disease of Bone ... and formation of bone ... • Caused by ( ... more (polystotic) bones ... pelvis, and long bones
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long bones ... • Differentiate ... BrighamChiefs #Bone ... #diagnosis #causes
Bone Lesion on X-Ray - Differential Diagnosis Algorithm Exostotic • Osteochondroma Asymptomatic &/or Non-Active Bone Scam •
Bone Lesion on X-Ray ... /or Non-Active Bone ... • Unicameral Bone ... • Aneurysmal Bone ... #Orthopedics #Causes
Primary Bone Tumors - Differential Diagnosis Algorithm Metastatic - Most common tumour in adults - Breast
Primary Bone Tumors ... - Differential ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Orthopedics #Causes
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - Differential ... Diagnosis Algorithm ... Miscellaneous - Bone ... Hyperthyroid, Bony ... #causes #endocrinology
Pancytopenia - Differential Algorithm / Schema - Bone Marrow Failure - Bone Marrow Infiltration - Sequestration / Destruction #Pancytopenia #Differential
Pancytopenia - Differential ... Algorithm / Schema ... - Bone Marrow ... Failure - Bone ... #Algorithm #Schema
Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Thrombocytopenia - Differential ... Diagnosis Algorithm ... production: • Bone ... suppression • Bone ... marrow failure • Bone
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
excessive bone ... turnover -> Incr bone ... MSK • Deformed bones ... Lytic lesions make bones ... of middle ear bones
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
synthesized in: liver, bone ... • softening of bones ... of feet, thigh bones ... : Inhibitor of bone ... Skeletal: - Bone
Hand X-Ray Anatomy and Interpretation Checklist 1. Soft tissues - Look carefully at the soft tissue over
tissue over all the bones ... Bones - All the ... bones of the hand ... in between the bones ... to the carpal bones
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