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diagnosis treatment differential nephrology syndrome dermatology pharmacology clinical neurology cardiology gastroenterology hematology rheumatology urine criticalcare hepatology infections microscopy acute infectiousdiseases
Granular & “Muddy Brown” Casts on Urine Microscopy A. Finely granular cast B. slightly coarser granular cast
Granular & “Muddy Brown ... ” Casts on Urine ... (c) and muddy brown ... of mb granular casts ... Granular #MuddyBrown #Casts
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy - Casts ... Acellular Casts ... • Hyaline Casts ... • "Muddy Brown ... " Casts - Strongly
Muddy Brown Granular Casts three ways - Brightfield, Darkfield, Phase Contrast. Dr. Vipin Varghese @vipvargh #Muddy #Brown #Granular
Muddy Brown Granular ... Casts three ways ... vipvargh #Muddy #Brown ... #Granular #Casts
Examples of varying granular and granular/waxy mixed casts: A: coarse granular/broad-waxy (and surrounding white blood cells);
granular/waxy mixed casts ... granular/muddy brown ... C and D: muddy brown ... Granular #MuddyBrown #Casts
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
microscopy • Red cell casts ... • White cell casts ... infection • Hyaline casts ... disease • Granular casts ... disease • “Muddy brown
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
urinalysis, labs - Management ... white blood cell casts ... renal tubular cell casts ... or pigmented casts ... renal biopsy - Management
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... "Muddy-brown" heme-granular ... casts are seen ... 34t5DgJ #Urinary #Casts
Infant UTI Algorithm (<8 weeks of age) Emergency Medicine Cases @EMCases #Infant #Pediatric #UTI #Algorithm #Diagnosis #Management #UrinaryTractInfection
Infant UTI Algorithm ... Emergency Medicine Cases ... Pediatric #UTI #Algorithm ... #Diagnosis #Management
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... proteinuria, granular casts ... Nephritis #AIN #Algorithm
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm Nail Plate - Pitting • Psoriasis • Alopecia Areata Nail
Differential Diagnosis Algorithm ... White / Yellow-Brown ... Discoloration - Brown ... Differential #Diagnosis #Algorithm ... #causes
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