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diagnosis differential nephrology aki rheumatology acute injury kidney types workup acutekidneyinjury allergy comparison cryoglobulinemia cryoglobulins gammopathy glomerular hypersensitivity mgrs monoclonal
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #Vasculitis #differential ... #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Necrotizing glomerulonephritis ... • Glomerulonephritis ... tract, and often causes ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... - Small vessel vasculitis ... Post-infectious glomerulonephritis ... tubular necrosis (causes ... Kidney #Injury #Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
rhabdo/TLS) Causes ... related) - Glomerulonephritis ... or vasculitis — ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... osmolarity If cause ... and signs • Glomerulonephritis ... / Vasculits: ANCA ... #AKI #Workup #Algorithm
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... Post-streptococcal glomerulonephritis ... allergy #table #classification
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... workup #diagnosis #glomerulonephritis
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... Clinical Clues: ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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