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differential causes hematology workup rheumatology disease management deficiency glomerular glomerulonephritis hemolytic nephrology nephrotic pancytopenia pulmonary abscess agglutinin allergy anca approach
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... #Diagnosis # ... IM #Rheum #Vasculitis ... #Vessel #Size #Classification ... #Differential #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... cardiac valve, vasculitis ... #hematology #testing
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... • Symptoms of anemia ... anemia • Cold ... Positive Coombs testing ... temperatures by fixing complement
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... Algorithm Low ... #MCV #Classification ... #Differential #Diagnosis ... #Algorithm #Causes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Differential Diagnosis ... against MPO • Complement ... differential #diagnosis ... #rheumatology #classification
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... Algorithm Decreased ... Megakaryopoiesis • Aplastic Anemia ... HUS • DIC • Vasculitis ... #Algorithm #Causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... #Classification ... #Differential #Diagnosis ... #Algorithm #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... perfringens - Complement-Mediated ... immune-complex hemolytic anemia ... #Algorithm #Causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Labs/Diagnosis: ... • Low serum C4 complement ... • Vasculitis ... Cryoglobulins #diagnosis ... #types #classification
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