16 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Malar (butterfly) Rash ... endothelium) & Decr blood ... pathophysiology #diagnosis #signs
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemorrhage, which are ... Autoimmune Vasculitis (lupus ... : • Complete blood ... cryoglobulins • Skin
Differentiating Features Between Central and Peripheral Cyanosis

Mechanism - Arterial destauration
Sites - Skin, mucous membrane of oral
Temperature - Warm ... therapy - Pulmonary cause ... Sites - Only skin ... Central #Peripheral #Comparison ... #Signs #Symptoms
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... - If present, are ... #sle #comparison ... #table #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... neutrophils in the blood
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... • Hemorrhagic Bullae ... vasculitis (inflamed blood ... #diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... are asthma, allergy ... organ-specific signs ... symptoms (eg, skin
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
Management of Purulent skin ... abnormal white blood ... infection such as bullae ... , skin sloughing ... including those caused
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... onset [33-74%] • Blood ... CD4+/CD8+ ratio are ... Dermatomyositis #rheumatology