17 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes Heart ... erythematosus #signs ... #symptoms #diagnosis
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... - If present, are ... sle #comparison #table
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
SKIN RASHES ... Skin rashes ... including infections, heat ... fever and systemic signs ... petechiae; #purpura; #rash
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
spasm - legs, arms ... Rash: • Small ... blisters on the skin ... → Syncope • Signs ... /Symptoms: - Lightheadedness
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
Management of Purulent skin ... , tachycardia (heart ... infection such as bullae ... , skin sloughing ... including those caused
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... secondary syphilis are ... faint that they are
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
repeated exposure to heat ... centrifugum • A chronic skin ... gyratum repens • A skin ... • Causes are multiple ... Erythemas #comparison #table
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
incidence in lung>heart ... EBV viral load, signs ... to 50% of PTLD cases ... transplantation are ... Lymphoproliferative #Disorders #oncology