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diagnosis rheumatology differential comparison dermatology hematology leukemia management syndrome vasculitis acute autoimmune chronic classification clinical cll complications druginduced endocarditis erythematosus
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation on skin ... pathophysiology #diagnosis #signs ... #symptoms #complications
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... Discontinuation of causal ... - If present, are ... #table #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus ... #dermatology #oncology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... secondary syphilis are ... faint that they are
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
are not caused ... Self-limiting, chronic but stable ... nodes: 13-15%, skin ... (16-32%): lupus ... Diagnosis #Management #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... mucositis - Rash ... Presentation - Systemic Symptoms ... purpura: strong sign ... vasculitis, and SLE
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
spasm - legs, arms ... fatigue Heat Rash ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... differential #diagnosis #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... diagnosis #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... When Cancer Cells are ... CLL -> Invade Skin ... Leukemia #Hematology #Oncology
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