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lupus systemic symptoms antinuclear autoimmune classification extrarticular joint management mimickers myopathy pain patterns vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(SLE), Sjogren's ... , Sjögren Syndrome ... , Interstitial Pulmonary ... #rheumatology #diagnosis ... #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... Vasculitis (e.g. ... #joint #pain #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Diagnosis: • ANCA-associated ... Still disease, ... Sjogren syndrome ... syndrome Arthritis ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Diagnosis and Lupus ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... #Diagnosis #autoantibodies ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #signs #symptoms ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... multisystemic disease ... Syndrome Diagnosis ... demyelinating disease ... #Syndrome #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... rheumatic diseases ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
lung disease Malignancy ... lung disease • ... lung disease • ... skeletal muscle disease ... #Myopathy #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... rheumatic diseases ... disease, and ocular ... #Differential #Diagnosis ... #Rheumatology
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