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differential vasculitis lupus management patterns workup antibody arthritis autoimmune conditions cryoglobulinemia cryoglobulins extrarticular igg4 laboratory myopathy myositis pain phenotypes related
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... • Rheumatic Diseases ... , Interstitial Pulmonary ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... connective tissue disease ... #ANCA #Antineutrophil ... #antibodies #diagnosis ... diseases
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Diseases: • Homogeneous ... tissue disease ... (SLE), Systemic ... #Antibodies #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... : • ANCA-associated ... • (-) ANA + (+ ... #Diagnosis #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... , SLE, Rheumatic ... #differential #diagnosis ... #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... with auto-immune diseases ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... (Granulomatous disease ... : Systemic rheumatic ... diseases, such ... LFT • ESR • ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic ... SLE) - Antinuclear ... exclude inflammatory disease ... connective-tissue disease ... #Disease #Rheumatoid
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... demyelinating disease ... peripheral Thyroid Disease ... Tracheobronchial disease
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... biliary, renal, lung ... (antinuclear antibodies ... IgG4 #Related #Disease
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