10 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... Diseases: • Homogeneous ... tissue disease ... #Antibodies #ANA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... ) • Systemic lupus ... #Antinuclear #Antibody ... #antibodies #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... diseases (i.e. ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Rheumatic ... • Interstitial lung ... , SLEPulmonary ... Rheumatic fever ... stenosis - Rheumatic
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... Association with disease ... with auto-immune diseases ... #diagnosis #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Diseases • Septic ... • Systemic lupus ... SLE) - Antinuclear ... antibody (ANA) ... #Disease #Rheumatoid
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
disease, and ocular ... (Granulomatous disease ... : Systemic rheumatic ... diseases, such ... as systemic lupus
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Elevated serum rheumatoid ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... (SLE), rheumatoid
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: • Systemic rheumatic ... diseases, such ... disease, drug reactions ... most important diseases ... disease, and ocular