10 results
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... tissue disease ... (SLE), Sjogren's ... #Antibodies #ANA ... #diagnosis #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Sjogren's ... , Interstitial Pulmonary ... #Antibodies #ANA ... #diagnosis #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... connective tissue disease ... 90% • Anti-GBM disease ... #antibodies #diagnosis ... diseases
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... with disease activity ... with auto-immune diseases ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
disease, and ocular ... Diagnosis: Systemic ... rheumatic diseases ... , and SLE) • Urinalysis ... differential #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Decade Skin Disease ... Diagnosis: • ANCA-associated ... diseases (i.e. ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... multisystemic disease ... Syndrome Diagnosis ... demyelinating disease ... #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis: • Systemic ... rheumatic diseases ... disease, and ocular ... #Differential #Diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Interstitial lung ... , SLEPulmonary ... Vasculitis (e.g. ... #joint #pain #differential ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
lung disease Malignancy ... lung disease • ... lung disease • ... skeletal muscle disease ... myocarditis Other Diseases