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differential classification lupus management symptoms antibodies aortitis associations conditions connectivetissuediseases cryoglobulinemia cryoglobulins ctild extrarticular ild joint lungdisease patterns table testing
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Rheumatic Diseases ... (SLE), Sjogren's ... • Rheumatic Diseases ... , Interstitial Pulmonary ... #patterns #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... PSS: Sjogren syndrome ... RA: rheumatoid arthritis ... SLE : systemic ... #Rheumatology #
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Nodosa (PAN), ANCA ... (rare) • Rheumatic ... (IgG4-RD), Rheumatoid ... erythematosus (SLE ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic ... • Interstitial lung ... , SLE, Rheumatic ... stenosis - Rheumatic ... #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... (20%) Renal disease ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... fever) and laboratory ... vasculitis, rheumatoid ... syndrome Arthritis ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
respectively, having rheumatoid ... Elevated serum rheumatoid ... (SLE), rheumatoid ... arthritis, Sjögren's ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Behçet Syndrome ... : Systemic rheumatic ... LFT • ESR • ANA ... , and SLE) • Urinalysis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... syndrome (Clinical ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Syndrome Diagnosis ... MALT Lymphoma • Lung ... #Syndrome #Rheumatology
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