12 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Vasculitis: • ... Renal-limited vasculitis ... #Antinuclear #Antibody ... diseases
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(SLE), Sjogren's ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #diagnosis #differential
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Diagnosis for Pulmonary ... vasculitis (Eosinophilic ... vasculitis (IgA-associated ... vasculitis, Behcet ... diagnosis #nephrology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
less common diseases ... • Sjögren syndrome ... disease • Multiple ... spectrum disorder • ANCA-associated ... vasculitides
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
disease, and ocular ... Vasculitis: + MPO-ANCA ... : • Behçet Syndrome ... Diagnosis: Systemic ... differential #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #systemic #erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Diagnosis: • Systemic ... • Behcet syndrome ... #Differential #Diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Interstitial lung ... , SLEPulmonary ... Neurologic system ... Vasculitis (e.g. ... #diagnosis #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... ) • Cutaneous vasculitis ... Vasculitis: • ... #Syndrome #Rheumatology