14 results
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... lung disease ... lupus erythematosus ... #vasculitis #differential ... #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... • Autoimmune diseases ... lupus erythematosus ... classification #rheumatology ... #vasculitis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
lupus erythematosus ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
disease, and ocular ... Diagnosis: Systemic ... lupus erythematosus ... differential #diagnosis ... #rheumatology #
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Diagnosis for Pulmonary ... vasculitis (Eosinophilic ... vasculitis, Behcet ... disease, Cryoglobulinemia ... lupus erythematosus
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... associated vasculitis ... : IgG4-Related Disease ... lupus erythematosus ... #Diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... lupus erythematosus ... Vasculitis: • ... Renal-limited vasculitis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
of Systemic Lupus ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #SLE #systemic ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... demyelinating disease ... ) • Cutaneous vasculitis ... Vasculitis: • ... #Rheumatology #