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patterns testing anca classification cytoplasmic dermatology diseases glomerulonephritis management petechiae petechial physicalexam progressive rapidly rash sjogrens syndrome vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... #Antinuclear #Antibody ... #antibodies #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... With associated pulmonary ... #differential # ... diagnosis #algorithm ... #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Scl70 (in some cases ... #Antinuclear #Antibody ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (ANA) ANA or Anti-NucIear ... Antibody refers ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... pattern: • SjS, SLE ... #Antinuclear #Antibody ... #Patterns #differential ... #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... antibodies, antineutrophil ... • Abdominal ultrasound ... #Diagnosis #Algorithm ... #Causes #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... ) pattern: antibodies ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
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