Bursitis diagnosis sle pulmonary ultrasound causes rheumatology antinuclear algorithm testing antibody hematology anca patterns ana antibodies management syndrome sjogrens

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ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

ANA (Antinuclear ... • Sjögren syndrome ... #Antinuclear #Antibody ... #antibodies #diagnosis ... #rheumatology #

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... : The ANA patterns ... ), Sjogren's Syndrome ... #Antibodies #ANA ... #patterns #rheumatology

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

ANA Patterns and ... ), Sjogren's Syndrome ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology

Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
• Homogeneous pattern:
-

Antinuclear Antibody ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology

Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern:
• SLE, SSc, AIH, JIA
• dsDNA, chromatin,

Antinuclear Antibody ... pattern: • SLE ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #diagnosis #rheumatology

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

Sjogren's Syndrome ... overlaps with RA, SLE ... Syndrome Diagnosis ... #Syndrome #Rheumatology ... #Diagnosis #Management

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

often causes arthritis ... ) pattern: antibodies ... ) pattern: is usually ... SLE) • Urinalysis ... #rheumatology #

Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40

such as: • SLE ... Most common • Sjogren ... Nonspecific ↑ ESR, CRP, ANA ... Polychondritis #rheumatology ... #diagnosis #management

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