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differential vasculitis classification systemic antibody antineutrophil aortitis arthritis autoantibodies cryoglobulinemia cryoglobulins disease laboratory table testing types vasculitides workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Rheumatic Diseases ... SLE), Sjogren's ... • Rheumatic Diseases ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... SLE), Sjogren's ... #Antibodies #ANA ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... erythematosus ... • Sjögren syndrome ... #antibodies #diagnosis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
), ANCA associated ... vasculitis (rare) • Rheumatic ... (IgG4-RD), Rheumatoid ... erythematosus ( ... SLE), Sarcoidosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... searched for when ANA ... and Sjogren Anti-SSB ... #diagnosis #rheumatology ... #table #ANA
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... : • ANCA-associated ... vasculitis, rheumatoid ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... : Systemic rheumatic ... ) pattern: antibodies ... SLE) • Urinalysis ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Laboratories Studies in Rheumatic ... SLE) - Antinuclear ... obtained when rheumatoid ... ) #Rheumatic ... #Disease #Rheumatoid
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
respectively, having rheumatoid ... Elevated serum rheumatoid ... DDX: • ANCA (Antineutrophil ... erythematosus ( ... SLE), rheumatoid
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
: • Systemic rheumatic ... as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... often causes arthritis ... #Rheumatology
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