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differential nuclear antineutrophil arthritis classification cytoplasmic diseases laboratory management rheumatic rheumatoid sjogrens syndrome vasculitides vasculitis workup
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... in drug-induced SLE ... #Antinuclear #Antibody ... #antibodies #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... : The ANA patterns ... #Antibodies #ANA ... #patterns #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... pattern: • SLE ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... ) pattern: antibodies ... ) pattern: is usually ... SLE) • Urinalysis ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
) - Antinuclear ... antibody (ANA) test ... ACE level, CXR, ANCA ... multiple myeloma) • ANA ... #testing #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Hypocomplementemia • Can cause ... Vasculitis: • 7%, Cryoglobulinemia ... Sjogrens #Syndrome #Rheumatology
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