Bursitis diagnosis sle ultrasound clinical abdominal pulmonary appendicitis rheumatology syndrome disease antinuclear signs management sjogrens systemic

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Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

- Summary Antinuclear ... heart block • Sjogren ... #Summary #diagnosis ... #rheumatology # ... management

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

likely it will be clinically ... ), Sjogren's Syndrome ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #diagnosis #differential

Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin

Clinical Features ... Demyelinating syndromes ... valve lesions Abdominal ... #signs #symptoms ... #diagnosis #rheumatology

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

and Systemic lupus ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis ... #rheumatology #

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

Sjogren's Syndrome ... overlaps with RA, SLE ... Syndrome Diagnosis ... #Syndrome #Rheumatology ... #Diagnosis #Management

Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
• Young

Systemic disease ... • Nonsurgical abdominal ... #diagnosis #management ... #signs #symptoms ... #rheumatology #

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

- GI tract: abdominal ... purpura: strong sign ... Supply gut -> abdominal ... vasculitis, and SLE ... #rheumatology #

Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,

as SLE, atherosclerotic ... purpura: Strong sign ... multiplex • GI tract: Abdominal ... gut involvement, abdominal ... #Rheumatology

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