94 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... antibody) - P-ANCA ... Hydralazine-induced ANCA ... @AnnKumfer #ANCA
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antibody) and ANCA ... - Anti-U1-RNP ANCA-Associated ... 80-90%) > MPO - ANCA ... disease - MPO>PR3 - ANCA ... Antinuclear #Antibody #ANCA
Pathogenesis of ANCA-associated vasculitis

Dr. Muner Mohamed @MunerMohamed1 

#ANCA #vasculitis #pathophysiology #nephrology
Pathogenesis of ANCA-associated ... MunerMohamed1 #ANCA ... pathophysiology #nephrology
Approach to managing Glomerulonephritis (GN) in children. 

ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
ANCA, antineutrophil ... antibodies; c-ANCA ... hypertension; p-ANCA ... Glomerulonephritis #Algorithm #Nephrology
Glomerulonephritis - Differential Diagnosis Framework
ANCA:
 • C-ANCA: GPA (Wegener's)
 • P-ANCA: Microscopic Polyangiitis, Eosinophilic GPA (Churg
Diagnosis Framework ANCA ... : • C-ANCA: GPA ... Wegener's) • P-ANCA ... differential #diagnosis #nephrology
Renal diseases associated with endothelial injury@NatRevNeph
#hemolyticuremicsyndrome #lupusnephritis #anca #Visualabstract #nephrology
lupusnephritis #anca ... Visualabstract #nephrology
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
ANCA Associated ... MPA → usually p-ANCA ... EGPA → ANCA in ... 40-50% P-ANCA ... (MPO) C-ANCA (
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... polyangiitis) - ANCA-negative ... testing: anti-ANCA ... , anti-GBM ab, ANA ... differential #diagnosis #nephrology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
VESSEL VASCULITIS: ANCA ... Associated - ANCA ... Granulomas - ANCA ... 80-90% have PR3-ANCA ... (Commonly MPO-ANCA