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ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... antibody) - P-ANCA ... Associated #Vasculitis #CANCA ... #PANCA #MPO #PR3
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Presentation (Pulmonary ... Diagnosis for Pulmonary ... testing: anti-ANCA ... @PulmPEEPs #Pulmonary
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
With associated pulmonary ... Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA,
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... Associated - ANCA ... Granulomas - ANCA ... glomerulonephritis and/or pulmonary ... arthritis, obstructive pulmonary
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Summary Autoimmune ANCA ... Although pulmonary ... Auto-antibodies: ANCA ... differential #diagnosis #management
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... glomerulonephritis 90%: - ANCA ... Double Positive (ANCA ... Kumfer @AnnKumfer #Pulmonary
Pulmonary Renal Syndrome: Investigations and Management #Pulmonary #Renal #Syndrome #Diagnosis #Workup #Management
Pulmonary Renal ... Investigations and Management ... #Pulmonary #Renal ... Diagnosis #Workup #Management
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antibody) and ANCA ... 80-90%) > MPO - ANCA ... MPO: 75-80% - ANCA ... disease - MPO>PR3 - ANCA ... Antinuclear #Antibody #ANCA
Pulmonary Hypertension Group Classification #Diagnosis #Management #Pulmonary #Hypertension #PHTN #Group #Classification #Curbsiders
Pulmonary Hypertension ... Classification #Diagnosis #Management ... #Pulmonary #Hypertension
Acute Pulmonary Embolism - Management Algorithms - Hemodynamically Stable Patients - Hemodynamically Unstable Patients - Dr. Eric
Acute Pulmonary ... Embolism - Management ... EricsMedicalLectures/ #Pulmonary ... Embolism #acutePE #Management
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