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Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD EMPA-REG ... SGLT2i in HF and CKD ... CANVAS - Canagliflozin ... SGLT2i in HF and CKD ... #CKD
#VisualAbstract for #Lancet trial #CANVASR #SGLT2i #Canagliflozin "Canagliflozin and renal outcomes in type 2 diabetes: results from
#Lancet trial #CANVASR ... results from the CANVAS
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
Definitions of AKI, CKD ... , AKD Acute Kidney ... Kidney Disease (CKD ... /CKD • No structural ... damage #AKI #CKD
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sensitive) • AKI, AKD ... rapidly progressive CKD ... sterile pyuria, WBC casts ... proteinuria, granular casts
Causes of Polyneuropathy - Differential Diagnosis Algorithm • Metabolic: DM, Hypothyroidism, CKD, Cirrhosis, Nutritional deficiency •
Causes of Polyneuropathy ... Hypothyroidism, CKD ... Paraneoplastic, CTD ... Diagnosis #Algorithm #causes
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
- Hx of AKI/CKD ... rhabdo/TLS) Causes ... 21% - AKI on CKD ... Diagnosis #Algorithm #Causes
Oral Antihypertensive Medications - Selection by Comorbidities Comorbidities: • Stable Angina, HFpEF, HFrEF, AFib, TAA/Marfan, Aortic
Dissection • CKD ... , DM, ESRD, PKD
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
Clock for Staging CKD ... Staging CKD is ... calculating the eGFR, CKD ... cut-offs for each CKD ... Diagnosis #Nephro #CKD
Causes of Generalized Edema - Differential Diagnosis Algorithm Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... NSAlDs • AKI/CKD ... Diagnosis #Algorithm #Causes
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Type 2) • HRS-AKD ... - No other cause ... ascites • HRS-CKD ... - No other cause
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