18 results
diagnosis differential neurology rheumatology symptoms management algorithm barre classification complications guillain lupus msk sle acute agammaglobulinemia cardiology chloride cryofibrinogenemia cryoglobulinemia
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
vascular event -> Complete ... > Often mimics complete ... -> Complete hemicord ... #diagnosis #pathophysiology ... #signs #symptoms
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
adhesion of IgA complexes ... Formation of immune complexes ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Focal: Simple, Complex ... malformation, Aneurysm, Vasculitis ... vasoconstriction syndrome ... Diagnosis #Algorithm #Causes
Causes of ST Segment Elevation - Differential Diagnosis Framework STEMI: • Upsloping convex STE: "Pardee's sign" +
precedes the QRS complex ... discordant with the QRS complex ... S1Q3T3 pattern; complete ... or in-complete ... - Widened QRS complexes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... Glomerulonephritis #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Manifestations • Immune Complex ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
antigen-antibody complexes ... Viral replication causes ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... tract, and often causes ... : • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... Hyperviscosity Syndrome ... 20% Sjögren's syndrome
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation (complex ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
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