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diagnosis classification pediatrics rheumatology differential lupus symptoms table vasculitis allergy complications genetics iem immunology inbornerrors laboratory metabolism neonatology nicu signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... (SLE): Musculoskeletal ... Manifestations • Immune Complex ... #SLE #MSK #Musculoskeletal ... Complications #pathophysiology
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... metabolism, excluding complex ... connections and pathophysiology ... See the lab values ... #Neonatology #Peds
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... Systemic Lupus • Erythematosus ... (SLE) If bacterial ... Allergy #Immunology #pathophysiology
Systemic Lupus Erythematosus (SLE): Pathogenesis • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Systemic Lupus Erythematosus ... (SLE): Pathogenesis ... production of immune complexes ... Systemic #Lupus #Erythematosus ... #SLE #Pathophysiology
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
of lab values compiled ... See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #Neonatology #Peds
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings Parasomnias - Micro-arousal episodes during SWS -> Intense activation of
arousal but no complete ... Nightmares #Pediatrics #Peds ... #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation (complex ... Phenomenon #Lupus #SLE ... Manifestations #pathophysiology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Antigen-antibody complexes ... systemic lupus erythematosus ... Classification #Pathophysiology
Serious Bacterial Illness (SBI): 1) UTI and pyelonephritis Most common cause of SBI Accounts for 3-8% of uncharacterized fevers Female
presentation Urinalysis: LE ... (particularly complex ... seizure) #Diagnosis #Peds
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... diseases: - 10% SLE ... systemic lupus erythematosus ... (SLE), rheumatoid
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