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blood product reactions algorithm anemia aplastic b12 chf coagulation cobalamin dic differential diffuse disseminated heartfailure hfref intravascular iron lad lymphadenopathy
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... • CMV • HIV ... Lymphocytic Leukemia (CBC ... #Hematology #Oncology
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... → Inflammation causes ... ID) Treatment - IV ... endpoint of all-cause ... #management #cardiology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... , CTLA4 deficiency ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
thrombopoietin deficiency ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... • Common Causes ... • Labs: - CBC ... consider IM or IV ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... Causes purpura & ... Extremely rare - HIV ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
recipients w/ IgA deficiency ... Causes purpura & ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... TYPE IV RTA, TYPE ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic ... #Diagnosis #Management
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