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differential algorithm causes testing betadglucan chronic dysuria exposure falsepositives fungal fuo galactomannan imdsoaps infectiousdiseases limitations mnemonic nephrology pct procalcitonin proteinuria
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm Neoplasm: • NHL • Hodgkin's lymphoma • Leukemia • Solid
• Trauma Non-infectious ... Organ Specific Infection ... • Infectious ... Cholangitis • UTI ... disease Viral Infection
Procalcitonin Limitations - Situations where PCT can be misinterpreted: - Single value testing - AKI/CKD - Pancreatitis - Cancers/Neoplasms - Trauma -
Burns - Localized infections ... (e.g. ... SSTI, UTI) - Atypical ... Limitations #PCT #Diagnosis ... #Laboratory
Fever in the Returning Traveler - History Exposure History: • Street foods / Local water: entenc fever,
tattoos, piercings, injections ... immunodeficiency virus [HIV ... , RTI 7-21 days ... travellers' diarrhea, RTI ... #diagnosis #differential
"I MD SOAPS" Infectious Diseases Exposure History I - Immunization - Vaccination status (age-appropriate, comorbidities, travel, etc) M
"I MD SOAPS" Infectious ... Diseases Exposure History ... specific food (e.g ... protection, past STI ... InfectiousDiseases #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Exercise • Fever ... • UTI Orthostatic ... HSP • Post-infectious ... Protein deposition (eg
Diagnostic Tests for Select Patients with Dysuria Imaging is not necessary in most patients with dysuria, although
Diagnostic Tests ... a complicated UTI ... anatomic anomaly (e.g ... positive family history ... abscess, relapsing infection
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 1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Other +s: PCP, Histo ... formulations (eg ... surfaces, Albumin, Infections ... Spec 81% for dx ... FalsePositives #Laboratory
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