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differential hematology causes management algorithm cardiology workup disorders infectiousdiseases thrombocytopenia acidosis activation adrenalmass afib anticoagulation arthritis atlas autoimmune bleed bleeding
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
CHA2DS2VASc vs HAS-BLED ... Bleeding history/anemia ... ) 1 #CHADS2 #CHADS2VASc ... Anticoagulation #AFib ... #Diagnosis #Hematology
Approach to ECGs - Tachy/Bradyarrhythmias Tachyarrhythmias - HR > 100 Wide (1) VT - DANGER (2)
Approach to ECGs ... abberancy - N B Afib ... (2) Sick Sinus Syndrome ... bradyarrhythmia #ECG ... #EKG #diagnosis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #hematology #anemia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... aciduria, Drugs (e.g ... Reticulocytosis, MDS ... #Differential #Diagnosis ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #Causes #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Liver Disease, MDS ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
- Differential Diagnosis ... Releasing Carcinoma (e.g ... Other Source (e.g ... Polycystic Ovarian Syndrome ... #Algorithm #Endocrinology
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