14 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Special cases (e.g ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Complex Regional Pain Syndrome (CRPS) - Treatment
Non-Pharmacologic:
 • Education
 • Physical & occupational therapy
 • Psychology
Treatment Non-Pharmacologic ... Psychology referral (e.g ... antidepressants (e.g ... Bisphosphonates (e.g ... #Treatment #Management
Cyclic Vomiting Syndrome - Treatment
Acute Treatment:
 • Abortive Therapy: Sumatriptan (5-HT / serotonin agonist), Aprepitant (neurokinin
, Antiemetics (e.g ... Pain control (e.g ... Treatment: • Non-Pharmacologic ... antidepressants (e.g ... #Treatment #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... antiinflammatory properties e.g ... #Rheumatology # ... diagnosis #management ... #Dermatology