29 results
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
eosinophils may also ... Lipid mediators (e.g ... Other mediators (e.g ... inflammatory mediators (e.g ... inflammatory cells • ANS
The Neuroanatomy and Physiology of Emotion
 • Thalamus
 • Primary and Association Cortices
 • The Prefrontal
• Thalamus • Primary ... decision making (e.g ... Nervous System (ANS ... ) -> The ANS automatically ... emotional stimulus (e.g
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... quadrant discomfort Signs ... autoimmune disease (e.g ... Elevated ALP 2. ... specific ANAs (e.g
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... (for secondary APS
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
function test, ANA (e.g ... not required in all ... unclear, or if a primary ... hematologic disorder ... #Workup #hematology
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia

If the patient is unconscious, signs of cardiac
is unconscious, signs ... cardiac ischaemia primarily ... 12-lead ECG machine ... CM5 continuous ECG ... Obtain a 12-lead ECG
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... diagnosis #workup #hepatology
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... nipple-like mass e.g ... , the plateau. e.g ... supply by fluid, e.g
Modified dengue severity classification, PAHO/WHO
Dengue without warning signs - DNWS:
 • Person who lives or has
without warning signs ... also include any ... attending physician (e.g ... nervous system [CNS ... > 1000 IU), CNS