36 results
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
r/o hemorrhage and ... Cardioembolic: • ECG ... +/- TEE (high Afib ... v Holter (r/o Afib ... workup #diagnosis #checklist
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Differential Diagnosis and ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... malignant syndrome (e.g ... hyperthermia crisis (late sign ... Anesthesiology #Anesthesia #Checklist
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... • Infection (e.g ... Infection (Forearm/Hand ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL and ... suspected) • In case ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology