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diagnosis management differential neurology syndrome treatment rheumatology aptt barre cardiology coagulation guillain lupus prolonged pt signs sle symptoms algorithm anemia
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... factor activity (e.g ... Plasma → Recheck abnormal ... clotting test (e.g ... #pathophysiology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Increased Requirement (e.g ... • Rule out B12 and ... Diagnosis #Algorithm #Causes ... #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... amyloidosis #Abnormal ... #differential #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential #hematology
Wolff–Parkinson–White syndrome (WPW) is one of several disorders of the electrical system of the heart that
WPW is caused by ... presence of an abnormal ... between the atria and ... #Pathophysiology ... Cardiology #MedStudent #EKG
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
stagnant hypoxia (e.g ... carrying capacity (e.g ... hemoglobin (e.g ... cannot use oxygen (e.g ... #pathophysiology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL and ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... ischemia and/or ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis and ... study (aPTT may be normal ... in mild cases) ... hemophilia type (e.g ... Management #treatment #hematology
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