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diagnosis syndrome cirrhosis treatment algorithm biliary pbc primary rheumatology aih alcoholic autoimmune blood liver nephrology acquired activation ah apml bloodbank
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... ) Pathophysiology ... Diagnosis: Viral Hepatitis ... age • Monitor and ... Liver #Pregnancy #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
AST/ALT >1.5, and ... (e.g., severe upper ... use assessment (e.g ... laboratory tests (e.g ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
AST/ALT >1.5, and ... (e.g., severe upper ... use assessment (e.g ... laboratory tests (e.g ... #Diagnosis #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
autoimmune disease (e.g ... dryness of the eyes and ... Elevated ALP 2. ... specific ANAs (e.g ... Diagnosis #Algorithm #hepatology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
inflammation (eg ... been reported (eg ... (eg Viral) Management ... Histology Findings (eg ... #Hepatology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Management • ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... Syndrome #Diagnosis #Management ... #treatment #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... vascular disorder (e.g ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs and ... obstruction • ALP ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
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