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diagnosis management algorithm arthritis differential laboratory anemia approach causes cell cerebritis cns crisis disease disorders erythematosus hypercoagulable joint leukostasis lupus
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
• Provoked (e.g ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
joint trauma (e.g ... subchondral bone (e.g ... derangements (e.g ... Joint #Pain #MSK #rheumatology ... #approach #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Workup History ... function test, ANA (e.g ... or if a primary hematologic ... Diagnosis #Causes #Workup ... #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
of substrate (e.g ... iron), low EPO, and ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... cause ischemia and ... Lumbar Puncture, EEG ... (@neudrawlogy) and ... CNS #neurology #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG ... diagnosis #management #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... inflammatory disease (e.g ... Chemistry profile (e.g ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
anemia (MAHA) Pathophysiology ... confirm diagnosis and ... other pathology (e.g ... (short-acting, e.g ... Renal #Crisis #rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... neck region and ... nasal cavity, and ... Oncology #Diagnosis #Workup ... #Hematology
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