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diagnosis management algorithm causes oncology syndrome acquired als amyotrophic apml arteritis differentiation disorders distribution eosinophil eosinophilia erythematosus gca giantcell increased
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Neutrophils - Differential ... Solid Tumour (e.g ... Lung, Bladder, Colon ... pancytopenia, blast cells ... Algorithm #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... adsorption onto cancer cells ... Diagnosis #Management #treatment ... #hematology #differential
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
eosinophilia (common ... glucocorticoid treatment ... signs or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... Prednisone 5mg/kg ... initiation • Differential ... diagnosis #management #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Neutropenia - Differential ... hypertension and/or drug treatment ... Constitutional disorders, eg ... including white blood cell ... diagnosis #causes #hematology
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
Common Dermatological ... and pruritus (e.g ... Varies with site, (e.g ... ; pruritis #dermatology ... #rash #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... Endocrine disorders (e.g ... Kidney disease common
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
fasciculations Common ... EMG: LMN Signs in ... conditions listed in differential ... diagnosis column Treatment ... neurons - IV free radical
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... Scapula • Less common ... axial skeleton ... Bone marrow Treatment ... Diagnosis #Workup #Hematology
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