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diagnosis causes algorithm anomaly bleeding bruising congenital developmentaldelay erythematosus history lupus primarycare purpura rheumatology sle systemic thrombocytopenia
Causes of Congenital Anomalies - Differential Diagnosis Algorithm Malformation • Embryonic development failure or inadequacy (often multifactorial) Deformation
normal tissue (e.g ... (Syndromic) • ... • Association (e.g ... Algorithm #Causes #Peds ... #Pediatrics
Causes of Developmental Delay - Differential Diagnosis Algorithm Isolated Domain Delay - Reduced Respiratory Drive: • Cognitive
Developmental Delay - Differential ... (e.g. ... • Mechanical (e.g ... Algorithm #Causes #Peds ... #Pediatrics
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
infiltration (e.g ... , e.g. ... - Vasculitis, e.g ... Bruising #Causes #peds ... #differential #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... (e.g. thyroid disease ... vein thrombosis Hematologic
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... #History #peds ... #pediatrics #diagnosis
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