107 results
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... requirements 1. ... Shock #Shock #Pathophysiology ... diagnosis #algorithm #causes
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Difficile Infection (CDI ... Perforation) Pathophysiology ... Epidemiology: • #1 ... 10 mg/kg IV x 1 ... doi.org/10.1093/cid
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Treatment: 1) ... Amyl nitrite - causes ... Toxicity #Toxicology #Pathophysiology
Hydroxyurea - Pathophysiology and Benefits in Sickle Cell Disease
 • Decreases number of pain crises (
Hydroxyurea - Pathophysiology ... number of pain crises ... hospitalizations (2.4 vs. 1) ... Benefits #SickleCell #pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... #Pharmacology #Pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... - Erosions and crusts ... Management: 1. ... glucorticoids if 1) ... not feasible CMC
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... 1) Extensive cutaneous ... Causes: 1) Exfoliative
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Leishmaniasis Life Cycle 1) ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- BMP, cap, CBC ... rhabdo/TLS) Causes ... Atheroemboli — 1% ... Diagnosis #Algorithm #Causes
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
Echinococcus Life Cycle 1) ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc