11 results
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
of a possible neuropathy ... CIDP, chronic inflammatory ... HNPP, hereditary neuropathy ... #Diagnosis #Neurology ... #Neuropathy #Peripheral
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
of Peripheral Neuropathy ... Inflammatory/AI: CIDP ... #Peripheral #Neuropathy ... diagnosis #causes #neurology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
of peripheral neuropathy ... Vasculitis #Management #Rheumatology ... Cryoglobulinemic #Nephrology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
CANOMAD (Ataxia+neuropathy ... myopathy • Anti MAG neuropathy ... VEGF+M component+neuropathy ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary disease, and ocular ... weakness - Nerves: neuropathy ... ulcers, cutaneous, ocular ... Syndrome: - Ocular ... differential #diagnosis #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... erectile dysfunction, Neuropathic ... Manifestations #diagnosis #neurology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Sensory and/or motor neuropathy ... weakness • Nerves: Neuropathy ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular ... Differential #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... cranial nerve neuropathy ... system: small-fiber neuropathy ... multiplex, peripheral neuropathy ... Sjogrens #Syndrome #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
and Symptoms • Ocular ... Neurological: Entrapment neuropathy ... myelopathy, Peripheral neuropathy ... Symptoms #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Non-autoimmune rheumatologic ... • Peripheral neuropathy ... Erythematosus #Diagnosis #Rheumatology