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rheumatology hematology management myopathy myositis algorithm autoimmune creatine dehydrogenase erythematosus fever hodgkins kinase laboratory lactate ldh lupus lymphoma lymphomas lymphoproliferative
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
weakness • Elevated ... CK, +Anti-Jo, + ... CK, +Anti-Jo, + ... Myopathies #myopathy #differential ... #diagnosis #comparison
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Kinase - Causes of Elevated ... ): • PROXIMAL MUSCLE ... Neuromuscular disorders ... #CK #differential ... #diagnosis #rhabdomyolysis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... paralyses CNS Disorders ... associated with any symptoms ... #differential #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... #Classification
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Diagnosis Framework ... kinase levels are elevated ... #rheumatology #differential ... #diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... Bilateral signs and/or symptoms ... CSF pleocytosis, elevated ... infectious myelitis - Elevated ... management #neurology #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... ingestion • B symptoms ... Inflammatory marker elevated ... Immunohistochemical studies (to differentiate ... #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... erythematosus (SCLE ... permanent alopecia Differential ... sediment, and elevated ... Induced Lupus: • Symptoms
PFAPA Syndrome - Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis EPIDEMIOLOGY: PFAPA is the most common syndrome entailing
DIFFERENTIAL DIAGNOSIS ... Inflammatory markers are elevated ... The diagnosis of ... Recurrent episodes of muscle ... contributor to this disorder
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