15 results
diagnosis differential rheumatology disorders autoimmune causes erythematosus lupus management myopathy neurology orthopedics pathophysiology systemic vasculitis arthropathies arthropathy chronic complications cord
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... - Myositis ... Erythematosus #SLE ... #MSK #Musculoskeletal ... pathophysiology #signs #symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... Can also see mechanics
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... ): • PROXIMAL MUSCLE ... tissue disorder, SLE ... Inclusion body myositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... • Myalgia • Myositis ... erythematosus (SLE ... inclusion body myositis ... Diagnosis: • CK
Chronic Joint Pain - Differential Diagnosis Algorithm Intra-Articular - Bone • Stress
Differential Diagnosis Algorithm ... Fasciitis) - Muscle ... Delayed Onset Muscle ... Fibromyalgia • Myositis ... Intraarticular #MSK
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... Hyperreflexia - Muscle ... - Transverse myelitis ... Behcet disease - SLE ... differential #algorithm
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Differential Diagnosis Algorithm ... Erythematosus (SLE ... should have other symptoms ... Joint #Disorders #msk ... Differential #Diagnosis #Algorithm
Dysphagia - Differential Diagnosis Algorithm Oropharyngeal Dysphagia Esophageal Dysphagia • Upper 2/3 (striated muscle): stroke, NMJ
Differential Diagnosis Algorithm ... 2/3 (striated muscle ... disorders, ALS, MS ... muscular atrophy, SLE ... Lower 2/3 (smooth muscle
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... Very high serum CK
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... Bilateral signs and/or symptoms ... Evaluate for NMO, SLE ... Predictive of MS ... Disorders: - SLE
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