12 results
diagnosis differential rheumatology autoimmune erythematosus lupus management myopathy neurology orthopedics systemic vasculitis chronic complications cord creatine disorders elevated fractures fragility
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... - Myositis ... Myopathy (Also caused ... #MSK #Musculoskeletal ... pathophysiology #signs #symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... Can also see mechanics
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Subacute to Chronic Causes ... ): • PROXIMAL MUSCLE ... tissue disorder, SLE ... Inclusion body myositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... • Myalgia • Myositis ... erythematosus (SLE ... inclusion body myositis ... Diagnosis: • CK
Chronic Joint Pain - Differential Diagnosis Algorithm Intra-Articular - Bone • Stress
Differential Diagnosis Algorithm ... Fasciitis) - Muscle ... Fibromyalgia • Myositis ... Intraarticular #MSK ... #Orthopedics #Causes
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... Non-compressive Spinal Cord Causes ... - Transverse myelitis ... Behcet disease - SLE ... differential #algorithm
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Differential Diagnosis Algorithm ... Tumours - See ... Pain/Proximal Muscle ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... Bilateral signs and/or symptoms ... Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... statins - probably caused
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... erythematosus (SCLE ... • Transverse Myelitis ... Induced Lupus: • Symptoms
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